Since 4000 B.C. this region became inhabited. The Hittites were the dominant people in Anatolia around 1800 B.C. Ceramic remains were found in the neighbourhood of Sıktırma and Kömürlük Kası, between the towns of Tatar and Yayalar and in the neighbourhood of Gavur Kuyusu Ağaçbeyli. Around 1200 B.C. the Phrygians who came from the Balkan countries conquered the Hittite cities and settled in this region. Around 670 B.C. the Lycians destroyed the Kingdom of Phrygia and dominated the territory. The Lycians put coinage in circulation for the first time in history. They also built the road of the kings, which starts at Ephesos and Milet, leads through Sardes (capital ) and Uşak. This road crosses Central Anatolia, continues above the river Kızılırmak and arrives in Mesopotamia. One part of the road goes through the territory of Karahalli, very close to the bridge of Cılandras. Around 547 B.C. the Persian emperor Cyrus conquered the region. In 324 B.C. Alexander the Great wins the battle against the Persians and creates the State of Macedonia. In 260 B.C. the Kingdom of Pergama  is founded . From 132 B.C. to 395 A.C. the Roman Empire dominates the region. The town of Pepouza is founded in 165 A.C. The Byzantines dominate the region from 395 to 1072. After the war of Malazgirt in 1071 between the Seldjoukid Turks and the Byzantines, the Seldjouks are victorious. In the 13th century the Turks come to this region and found the town of Karahalli. Between the 13th and the 14th century the Germiyanogulları State dominates the region. From 1429 the Ottoman Empire dominates the territory. Since the war of independence in 1922 the region is part of the Republic of Turkey.